Verified Immunity. Informed Choice.

Advocating for Rabies Titer Testing as a verified alternative to over-vaccination for medically fragile and protected animals.

The Science of Verified Immunity

Moving from “Calendar-Based” Guesswork to “Evidence-Based” Protection.

1. The 0.5 IU/mL Threshold: The Global Benchmark

A Rabies Virus Antibody Titer (RVNA) isn’t just a “pass/fail” test; it is a precise measurement of your pet’s ability to neutralize the virus.

  • The WHO Standard: The World Health Organization (WHO) and the CDC recognize 0.5 IU/mL as the definitive “adequate response” to vaccination.

  • International Travel: This is the exact same standard required by “Rabies-Free” countries (like Hawaii, Japan, and New Zealand) for entry. If this level of immunity is trusted to protect entire island nations, it is more than sufficient for a pet living in Summit County.

  • The Reality: Many pets maintain levels far above 0.5 IU/mL for many years beyond their last booster. Re-vaccinating an animal that is already at or above this level provides zero additional protection.

2. Accredited Laboratories: Ensuring Accuracy

To maintain the highest level of public safety, our proposal requires that all titers be processed by accredited, gold-standard reference laboratories. We are advocating for the use of:

  • Kansas State University (KSU) Rabies Laboratory

  • Cornell University Animal Health Diagnostic Center

  • Auburn University College of Veterinary Medicine

These labs utilize the FAVN (Fluorescent Antibody Virus Neutralization) and RFFIT (Rapid Fluorescent Focus Inhibition Test) methods. These are the most rigorous tests available, ensuring that every “passing” result submitted to the County is scientifically irrefutable.

3. The Anamnestic Response: The “Memory” of Immunity

One of the most common misconceptions is that immunity “disappears” if a titer drops slightly. In reality, the immune system is dynamic.

  • Immune Memory: When a pet is vaccinated, their body creates “Memory B-cells.”

  • The Rapid Spike: If a pet with a passing titer is ever exposed to the rabies virus, these memory cells trigger an Anamnestic Response—a massive, rapid spike in antibody production that neutralizes the virus before it can take hold.

  • Long-Term Security: Research (by the Rabies Challenge Fund and others) proves that this “immunological memory” persists for many years, often for the life of the animal, making frequent re-vaccination of immune pets unnecessary.

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